Recombinant Human Cyclophilin D (rHuCyP-D)
英文全名
Recombinant Human Cyclophilin D (rHuCyP-D)英文又名
PPIF, Cyclophilin F, CyP-M, Rotamase F卵白布局
氨基酸序列
CSKGSGDPSS SSSSGNPLVY LDVDANGKPL GRVVLELKAD VVPKTAENFR ALCTGEKGFG YKGSTFHRVI PSFMCQAGDF TNHNGTGGKS IYGSRFPDEN FTLKHVGPGV LSMANAGPNT NGSQFFICTI KTDWLDGKHV VFGHVKEGMD VVKKIESFGS KSGRTSKKIV ITDCGQLSAccession
Gene ID
产物英文概述
CyP-D is a part of the peptidyl-prolyl cis-trans isomerase (PPIase) family. CyP-D accelerates the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. CyP-D is key component of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death.来历
Escherichia coli.份子量
Approximately 18.9 kDa, a single non-glycosylated polypeptide chain containing 178 amino acids.生物活性
No data available表面
Sterile colorless liquid.配方
Supplied as a 0.2 um filtered solution in PBS, pH7.4, with 1 mM DTT, 10 % glycerol.内毒素
Less than 0.1 EU/ug of rHuCyP-D as determined by LAL method.消融申明
贮存前提
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 6 months from date of receipt, -20 to -70 °C as supplied.- 3 months, -20 to -70 °C under sterile conditions after opening.参考材料
纯度
> 95 % by SDS-PAGE and HPLC analyses.SDS-PAGE电泳
